CRISPR technology has rapidly advanced in recent years, with new tools and clinical breakthroughs. Highlight the recent developments in CRISPR-based gene editing technology applications. Discuss the opportunities and ethical challenges these advancements present for healthcare and society.

CRISPR technology is an advanced gene editing tool which acts as a molecular scissor to cleave harmful gene (e.g. arranged) and replace them with target genes. It addresses the genetic cause of disease. CRISPR is also used to introduce desirable trait in organisms such as higher yield in plants & self-termination in mosquitoes. Recent developments → 1) CRISPR-CAS9 is used to treat forms of cancer such as blood cancer, home armed eh. 2) Used to correct gene defects pertaining to dysfunction of various body part. e.g. Sickle cell anaemia.

Way forward: As per Omvides Convention on Biothics - i Uphold plurality of humanity. ii Equitable access to treatments. iii Precautionary principle in genetic engineering.

— ISHAN BHATNAGAR · AIR 5